To install this package, start R and enter:
## try http:// if https:// URLs are not supported
source("https://bioconductor.org/biocLite.R")
biocLite("ALDEx2")
In most cases, you don't need to download the package archive at all.
ALDEx2
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Analysis Of Differential Abundance Taking Sample Variation Into Account
Bioconductor version: Release (3.5)
A differential abundance analysis for the comparison of two or more conditions. For example, single-organism and meta-RNA-seq high-throughput sequencing assays, or of selected and unselected values from in-vitro sequence selections. Uses a Dirichlet-multinomial model to infer abundance from counts, that has been optimized for three or more experimental replicates. Infers sampling variation and calculates the expected false discovery rate given the biological and sampling variation using the Wilcox rank test or Welches t-test (aldex.ttest) or the glm and Kruskal Wallis tests (aldex.glm). Reports both P and fdr values calculated by the Benjamini Hochberg correction.
Author: Greg Gloor, Ruth Grace Wong, Andrew Fernandes, Arianne Albert, Matt Links, Jia Rong Wu
Maintainer: Greg Gloor <ggloor at uwo.ca>
Citation (from within R,
enter citation("ALDEx2")):
Installation
To install this package, start R and enter:
## try http:// if https:// URLs are not supported
source("https://bioconductor.org/biocLite.R")
biocLite("ALDEx2")
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("ALDEx2")
| R Script | An R Package for determining differential abundance in high throughput sequencing experiments | |
| Reference Manual | ||
| Text | NEWS | |
| Text | LICENSE |
Details
| biocViews | Bayesian, ChIPSeq, DNASeq, DifferentialExpression, GeneExpression, Metagenomics, Microbiome, RNASeq, Sequencing, Software |
| Version | 1.8.0 |
| In Bioconductor since | BioC 3.0 (R-3.1) (3 years) |
| License | file LICENSE |
| Depends | methods |
| Imports | S4Vectors, IRanges, GenomicRanges, SummarizedExperiment, BiocParallel |
| LinkingTo | |
| Suggests | |
| SystemRequirements | |
| Enhances | |
| URL | |
| Depends On Me | |
| Imports Me | |
| Suggests Me | |
| Build Report |
Package Archives
Follow Installation instructions to use this package in your R session.
| Source Package | ALDEx2_1.8.0.tar.gz |
| Windows Binary | ALDEx2_1.8.0.zip |
| Mac OS X 10.11 (El Capitan) | ALDEx2_1.8.0.tgz |
| Source Repository | git clone https://git.bioconductor.org/packages/ALDEx2 |
| Package Short Url | http://bioconductor.org/packages/ALDEx2/ |
| Package Downloads Report | Download Stats |
Documentation »
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